Co-Director BioTechMed-Graz

Expertise

Prof. Robert Krause developed and expanded Clinical Infectious Diseases at Medical University of Graz. He is a physician scientist with special training in infectious diseases, internal medicine, and intensive care medicine. Prof. Krause investigates clinical aspects of fungal infections including biomarkers for earlier detection of fungal infections and risk stratification. Further topics of his research team include sepsis, foreign body associated infections, gastrointestinal infections, „antibiotic stewardship“ and „(re-) emerging infections“. Results of his team could be integrated in clinical routine and improved patient care, e.g. in patients with staphylococcus aureus bacteremia (final „Steirischer Qualitätspreis Gesundheit“). Currently his research group works on host-pathogen interactions in fungal infections and biomarker development in sepsis.
Prof Krause was President of the Austrian Society for Antimicrobial Chemotherapy (ÖGACH; 2016-2018) and is a board member of the Austrian Society for Infectious Diseases and Tropical Medicine and the ÖGACH. He was part of an EU project („abs-international“) and execute(d) projects funded by Austrian Research Promotion Agency (FFG) and the Austrian Science Fund (FWF).

Selected Publications

• Prattes, J; Schneditz, D; Prüller, F; Jaindl, E; Sauseng, N; Hoenigl, M; Schilcher, G; Krause, R. 1, 3-ß-d-Glucan testing is highly specific in patients undergoing dialysis treatment. J Infect. 2017; 74(1):72-80

• de With, K; Allerberger, F; Amann, S; Apfalter, P; Brodt, HR; Eckmanns, T; Fellhauer, M; Geiss, HK; Janata, O; Krause, R; Lemmen, S; Meyer, E; Mittermayer, H; Porsche, U; Presterl, E; Reuter, S; Sinha, B; Strauß, R; Wechsler-Fördös, A; Wenisch, C; Kern, WV. Strategies to enhance rational use of antibiotics in hospital: a guideline by the German Society for Infectious Diseases. Infection. 2016; 44(3):395-439

• Krause, R; Halwachs, B; Thallinger, GG; Klymiuk, I; Gorkiewicz, G; Hoenigl, M; Prattes, J; Valentin, T; Heidrich, K; Buzina, W; Salzer, HJ; Rabensteiner, J; Prüller, F; Raggam, RB; Meinitzer, A; Moissl-Eichinger, C; Högenauer, C; Quehenberger, F; Kashofer, K; Zollner-Schwetz, I. Characterisation of Candida within the Mycobiome/Microbiome of the Lower Respiratory Tract of ICU Patients. PLoS One. 2016; 11(5):e0155033-e0155033

• Krause, R; Zollner-Schwetz, I; Salzer, HJ; Valentin, T; Rabensteiner, J; Prüller, F; Raggam, R; Meinitzer, A; Prattes, J; Rinner, B; Strohmaier, H; Quehenberger, F; Strunk, D; Heidrich, K; Buzina, W; Hoenigl, M. Elevated levels of interleukin 17A and kynurenine in candidemic patients, compared with levels in noncandidemic patients in the intensive care unit and those in healthy controls. J Infect Dis. 2015; 211(3):445-451

• Rabensteiner, J; Theiler, G; Duettmann, W; Zollner-Schwetz, I; Hoenigl, M; Valentin, T; Leitner, E; Luxner, J; Grisold, A; Valentin, A; Neumeister, P; Krause, R. Detection of central venous catheter-related bloodstream infections in haematooncological patients. Eur J Clin Invest. 2015; 45(8):824-832

• Hoenigl, M; Duettmann, W; Raggam, RB; Huber-Krassnitzer, B; Theiler, G; Seeber, K; Prueller, F; Zollner-Schwetz, I; Prattes, J; Wagner, J; Wölfler, A; Krause, R. Impact of structured personal on-site patient education on low posaconazole plasma concentrations in patients with haematological malignancies. Int J Antimicrob Agents. 2014; 44(2):140-144

• Hoenigl, M; Raggam, RB; Wagner, J; Prueller, F; Grisold, AJ; Leitner, E; Seeber, K; Prattes, J; Valentin, T; Zollner-Schwetz, I; Schilcher, G; Krause, R. Procalcitonin fails to predict bacteremia in SIRS patients: a cohort study. Int J Clin Pract. 2014; 68(10):1278-1281

• Hoenigl, M; Wagner, J; Raggam, RB; Prueller, F; Prattes, J; Eigl, S; Leitner, E; Hönigl, K; Valentin, T; Zollner-Schwetz, I; Grisold, AJ; Krause, R. Characteristics of hospital-acquired and community-onset blood stream infections, South-East Austria. PLoS One. 2014; 9(8):e104702-e104702

• Pruller, F; Wagner, J; Raggam, RB; Hoenigl, M; Kessler, HH; Truschnig-Wilders, M; Krause, R. Automation of serum (1 -> 3)-beta-D-glucan testing allows reliable and rapid discrimination of patients with and without candidemia. MED MYCOL. 2014; 52(5): 455-461.

• Schilcher, G; Schneditz, D; Ribitsch, W; Horina, JH; Hoenigl, M; Valentin, T; Rosenkranz, AR; Krause, R. Loss of antimicrobial effect of trisodium citrate due to 'lock' spillage from haemodialysis catheters. Nephrol Dial Transplant. 2014; 29(4):914-919

• Buyle, FM; Metz-Gercek, S; Mechtler, R; Kern, WV; Robays, H; Vogelaers, D; Struelens, MJ. members of the Antibiotic Strategy International (ABS) Quality Indicators Team Development and validation of potential structure indicators for evaluating antimicrobial stewardship programmes in European hospitals. Eur J Clin Microbiol Infect Dis. 2013; 32(9):1161-1170 

• Hoenigl, M; Duettmann, W; Raggam, RB; Seeber, K; Troppan, K; Fruhwald, S; Prueller, F; Wagner, J; Valentin, T; Zollner-Schwetz, I; Wölfler, A; Krause, R. Potential factors for inadequate voriconazole plasma concentrations in intensive care unit patients and patients with hematological malignancies. Antimicrob Agents Chemother. 2013; 57(7):3262-3267

All Publications